CaMKII and Learning

<body topmargin=0 leftmargin=0 marginheight=0 marginwidth=0> <table cellpadding=0 cellspacing=0 border=0 height="100%"><tr> <td valign="top" width=12.5% BGCOLOR="#FFFFFF" TEXT="#080000"> <bR> <bR> </td> <td valign="top" width="100%" style=" border-top: 26px solid #FFFFFF; border-left: 63px solid #FFFFFF;border-right: 63px solid #FFFFFF;" BGCOLOR="#FFFFFF" TEXT="#080000"> <bR> <div> <TABLE BORDER="1" CELLPADDING="0" CELLSPACING="0" WIDTH="785" BORDERCOLORLIGHT="#808080" BORDERCOLORDARK="#FFFFFF" FRAME="BOX" RULES="ALL" HSPACE="0" VSPACE="0" > <tR> <tD VALIGN=TOP BGCOLOR=#DDDDDD HEIGHT= 76 ><NOBR><div> <A HREF="index.htm" TARGET="_top" TITLE="Silvalab"><B><IMG SRC="14860c470.png" border=0 width="780" height="71" ALIGN="BOTTOM" HSPACE="0" VSPACE="0"></B></A></div> </NOBR></tD> </tR> <tR> <tD VALIGN=TOP BGCOLOR=#BBBBBB HEIGHT= 30 ><NOBR><div> <B> </B><A HREF="projects.htm" TARGET="_top" TITLE="Projects "><B><IMG SRC="147e61190.png" border=0 width="97" height="25" ALIGN="BOTTOM" HSPACE="0" VSPACE="0"></B></A><A HREF="approaches.htm" TARGET="_top" TITLE="Approaches"><B><IMG SRC="147f61190.png" border=0 width="97" height="25" ALIGN="BOTTOM" HSPACE="0" VSPACE="0"></B></A><A HREF="publications.htm" TARGET="_top" TITLE="Publications"><B><IMG SRC="148061190.png" border=0 width="97" height="25" ALIGN="BOTTOM" HSPACE="0" VSPACE="0"></B></A><A HREF="personnel.htm" TARGET="_top" TITLE="Lab Members"><B><IMG SRC="148161190.png" border=0 width="97" height="25" ALIGN="BOTTOM" HSPACE="0" VSPACE="0"></B></A><A HREF="alcino.htm" TARGET="_top" TITLE="Alcino J. Silva"><B><IMG SRC="148261190.png" border=0 width="97" height="25" ALIGN="BOTTOM" HSPACE="0" VSPACE="0"></B></A><A HREF="funding.htm" TARGET="_top" TITLE="Awards"><B><IMG SRC="148361190.png" border=0 width="97" height="25" ALIGN="BOTTOM" HSPACE="0" VSPACE="0"></B></A><A HREF="positions.htm" TARGET="_top" TITLE="Open Positions"><B><IMG SRC="148461190.png" border=0 width="97" height="25" ALIGN="BOTTOM" HSPACE="0" VSPACE="0"></B></A><A HREF="aboutus.htm" TARGET="_top" TITLE="aboutus"><B><IMG SRC="148561190.png" border=0 width="97" height="25" ALIGN="BOTTOM" HSPACE="0" VSPACE="0"></B></A></div> </NOBR></tD> </tR> <tR> <tD VALIGN=TOP BGCOLOR=#6666CC HEIGHT= 20 WIDTH="781"><div>        <A HREF="index.htm" TARGET="_top" TITLE="Silvalab"><B>Home</B></A></div> </tD> </tR> </TABLE></div> <div> <TABLE BORDER="1" CELLPADDING="4" CELLSPACING="0" WIDTH="781" BORDERCOLORLIGHT="#330000" BORDERCOLORDARK="#FFFFFF" FRAME="BOX" RULES="ALL" HSPACE="0" VSPACE="0" BGCOLOR=#EEEEEE > <tR> <tD VALIGN=TOP BGCOLOR=#FFFFFF HEIGHT= 529 WIDTH="769"><bR> <div> <IMG SRC="106ddee10.jpg" border=0 width="478" height="225" ALIGN="BOTTOM" HSPACE="0" VSPACE="0"></div> <div> CaMKII and learning</div> <bR> <div> <B>Over the last 15 years our laboratory has engineered and analyzed a number of CaMKII mutations that helped to illuminate how this kinase regulates synaptic function and learning and memory. More recently, we have focused our attention on the  functional implications of the complex interactions between this kinase and post-synaptic density proteins, as well as on the role of this kinase in cortical memory formation.  The idea of these studies is to leverage the wealth of information concerning the beautifully intricate biochemistry of this kinase, in studies of synaptic mechanisms of learning and memory.</B></div> <bR> <bR> </tD> </tR> <tR> <tD VALIGN=TOP HEIGHT= 184 WIDTH="769"><bR> <div> For descriptions of our projects click on one of the links below...</div> <bR> <div> <A HREF="aging.htm" TARGET="_top" TITLE="Aging and Cognition">Aging and Cognition</A>   ·   <B>CaMKII and Learning</B>   ·   <A HREF="enhancements.htm" TARGET="_top" TITLE="Cognitive enhancements">Cognitive enhancements</A>   ·   <A HREF="cortical.htm" TARGET="_top" TITLE="Cortical memories">Cortical memories</A>   ·   <A HREF="recovery.htm" TARGET="_top" TITLE="Enhancing plasticity and recovery">Enhancing plasticity and recovery</A>   ·   <A HREF="ld.htm" TARGET="_top" TITLE="Learning disabilities">Learning disabilities</A>   ·   <A HREF="allocation.htm" TARGET="_top" TITLE="Memory Allocation">Memory Allocation</A>   ·   <A HREF="genes.htm" TARGET="_top" TITLE="Novel memory genes">Novel memory genes</A>   ·   <A HREF="schizophrenia.htm" TARGET="_top" TITLE="Schizophrenia">Schizophrenia</A>   ·   <A HREF="s2.htm" TARGET="_top" TITLE="Science of Science">Science of Science</A></div> </tD> </tR> <tR> <tD VALIGN=TOP BGCOLOR=#FFFFFF HEIGHT= 162 WIDTH="769"><bR> <bR> <bR> <bR> <div> <A HREF="projects.htm" TARGET="_top" TITLE="Projects ">Projects </A>   ·   <A HREF="approaches.htm" TARGET="_top" TITLE="Approaches">Approaches</A>   ·   <A HREF="publications.htm" TARGET="_top" TITLE="Publications">Publications</A>   ·   <A HREF="personnel.htm" TARGET="_top" TITLE="Lab Members">Lab Members</A>   ·   <A HREF="alcino.htm" TARGET="_top" TITLE="Alcino J. Silva">Alcino J. Silva</A>   ·   <A HREF="funding.htm" TARGET="_top" TITLE="Awards">Awards</A>   ·   <A HREF="pictures.htm" TARGET="_top" TITLE="Lab Pictures">Lab Pictures</A>   ·   <A HREF="positions.htm" TARGET="_top" TITLE="Open Positions">Open Positions</A>   ·   <A HREF="aboutus.htm" TARGET="_top" TITLE="aboutus">aboutus</A>   ·   <A HREF="contact_us.htm" TARGET="_top" TITLE="Contact us">Contact us</A></div> <bR> </tD> </tR> </TABLE></div> <bR> <div> <TABLE BORDER="0" CELLPADDING="2" CELLSPACING="1" WIDTH="531" BORDERCOLORLIGHT="#C0C0C0" BORDERCOLORDARK="#808080" FRAME="BOX" RULES="ALL" HSPACE="0" VSPACE="0" > <tR> <tD VALIGN=TOP HEIGHT= 267 WIDTH="525"><div>            </div> <bR> <bR> <bR> </tD> </tR> </TABLE></div> <bR> <bR> <bR> </td> </tr></table></body>