in vivo Imaging

<body topmargin=0 leftmargin=0 marginheight=0 marginwidth=0> <table cellpadding=0 cellspacing=0 border=0 height="100%"><tr> <td valign="top" width=12.5% BGCOLOR="#FFFFFF" TEXT="#080000"> <bR> </td> <td valign="top" width="100%" style=" border-top: 26px solid #FFFFFF; border-left: 63px solid #FFFFFF;border-right: 63px solid #FFFFFF;" BGCOLOR="#FFFFFF" TEXT="#080000"> <div> <TABLE BORDER="1" CELLPADDING="0" CELLSPACING="0" WIDTH="887" BORDERCOLORLIGHT="#808080" BORDERCOLORDARK="#FFFFFF" FRAME="BOX" RULES="ALL" HSPACE="0" VSPACE="0" > <tR> <tD VALIGN=TOP BGCOLOR=#DDDDDD HEIGHT= 88 ><NOBR><div> <B><IMG SRC="14d71e4a0.png" border=0 width="798" height="74" ALIGN="BOTTOM" HSPACE="0" VSPACE="0"><IMG SRC="152953530.jpg" border=0 width="83" height="83" ALIGN="BOTTOM" HSPACE="0" VSPACE="0"></B></div> </NOBR></tD> </tR> <tR> <tD VALIGN=TOP BGCOLOR=#BBBBBB HEIGHT= 30 ><NOBR><div> <B> </B><A HREF="index.htm" TARGET="_top" TITLE="Silvalab"><B><IMG SRC="154b61190.png" border=0 width="97" height="25" ALIGN="BOTTOM" HSPACE="0" VSPACE="0"></B></A><B> </B><A HREF="projects.htm" TARGET="_top" TITLE="Projects "><B><IMG SRC="147e61190.png" border=0 width="97" height="25" ALIGN="BOTTOM" HSPACE="0" VSPACE="0"></B></A><A HREF="approaches.htm" TARGET="_top" TITLE="Approaches"><B><IMG SRC="147f61190.png" border=0 width="97" height="25" ALIGN="BOTTOM" HSPACE="0" VSPACE="0"></B></A><A HREF="publications.htm" TARGET="_top" TITLE="Publications"><B><IMG SRC="148061190.png" border=0 width="97" height="25" ALIGN="BOTTOM" HSPACE="0" VSPACE="0"></B></A><A HREF="personnel.htm" TARGET="_top" TITLE="Lab Members"><B><IMG SRC="148161190.png" border=0 width="97" height="25" ALIGN="BOTTOM" HSPACE="0" VSPACE="0"></B></A><A HREF="alcino.htm" TARGET="_top" TITLE="Alcino J. Silva"><B><IMG SRC="148261190.png" border=0 width="97" height="25" ALIGN="BOTTOM" HSPACE="0" VSPACE="0"></B></A><A HREF="awards.htm" TARGET="_top" TITLE="Awards"><B><IMG SRC="148361190.png" border=0 width="97" height="25" ALIGN="BOTTOM" HSPACE="0" VSPACE="0"></B></A><A HREF="positions.htm" TARGET="_top" TITLE="Open Positions"><B><IMG SRC="148461190.png" border=0 width="97" height="25" ALIGN="BOTTOM" HSPACE="0" VSPACE="0"></B></A><A HREF="aboutus.htm" TARGET="_top" TITLE="aboutus"><B><IMG SRC="148561190.png" border=0 width="97" height="25" ALIGN="BOTTOM" HSPACE="0" VSPACE="0"></B></A></div> </NOBR></tD> </tR> <tR> <tD VALIGN=TOP BGCOLOR=#6666CC HEIGHT= 20 WIDTH="883"><div>  </div> </tD> </tR> </TABLE></div> <bR> <div> <TABLE BORDER="1" CELLPADDING="4" CELLSPACING="0" WIDTH="885" BORDERCOLORLIGHT="#330000" BORDERCOLORDARK="#FFFFFF" FRAME="BOX" RULES="ALL" HSPACE="0" VSPACE="0" > <tR> <tD VALIGN=TOP ROWSPAN=2 HEIGHT= 199 WIDTH="242"><div> Approaches:</div> <bR> <div> <A HREF="approaches64.htm" TARGET="_top" TITLE="Molecular Genetics"><B>Molecular Genetics</B></A></div> <div> <A HREF="approaches69.htm" TARGET="_top" TITLE="PRISM"><B>PRISM</B></A></div> <div> <A HREF="electrophysiology.htm" TARGET="_top" TITLE="Electrophysiology"><B>Electrophysiology</B></A></div> <div> <A HREF="approaches67.htm" TARGET="_top" TITLE="Neuroanatomy"><B>Neuroanatomy</B></A></div> <div> <B><IMG BORDER="0" SRC="Symb075c00b700f000000000.png" HEIGHT="16" WIDTH="24" ALIGN="bottom" HSPACE="0" VSPACE="0">in vivo Imaging</B></div> <div> <A HREF="behavior.htm" TARGET="_top" TITLE="Behavioral Analyses"><B>Behavioral Analyses</B></A></div> <div> <A HREF="mice_to_men.htm" TARGET="_top" TITLE="Bridging Mice and Men"><B>Bridging Mice and Men</B></A></div> <bR> <bR> <div> <B><IMG SRC="158ec1e30.jpg" border=0 width="193" height="227" ALIGN="BOTTOM" HSPACE="0" VSPACE="0"></B></div> <div> Max projection in vivo image stack of  neuron in retrosplinial cortex of Thy-1 GFP mice (from Balaji Jayaprakash)</div> <bR> </tD> <tD VALIGN=TOP ROWSPAN=2 WIDTH="621"><bR> <div> <IMG SRC="1586dddd0.png" border=0 width="221" height="221" ALT="2 photon image of retroplinial cortex courtesy of Rafal Czajkowski" ALIGN="BOTTOM" HSPACE="0" VSPACE="0"></div> <div> Retroplinial cortex (from Rafal Czajkowski)</div> <div> <I>in vivo</I> 2-photon imaging</div> <bR> <div> In vivo 2-photon laser scanning confocal imaging  allows time-lapse studies of single neurons in living mice. We are using this state-of-the-art imaging technique to study neuronal events responsible for the storage of memory in the neocortex. We are focusing our studies both on axonal and dendritic structural changes underlying memory, as well as on circuit properties of memory encoding in complex neocortical networks.</div> <bR> </tD> </tR> <tR> </tR> <tR> <tD VALIGN=TOP COLSPAN=2 HEIGHT= 76 WIDTH="865"><bR> <bR> <div> <A HREF="approaches64.htm" TARGET="_top" TITLE="Molecular Genetics">Molecular Genetics</A>   ·   <A HREF="approaches69.htm" TARGET="_top" TITLE="PRISM">PRISM</A>   ·   <A HREF="electrophysiology.htm" TARGET="_top" TITLE="Electrophysiology">Electrophysiology</A>   ·   <A HREF="approaches67.htm" TARGET="_top" TITLE="Neuroanatomy">Neuroanatomy</A>   ·   <B>in vivo Imaging</B>   ·   <A HREF="behavior.htm" TARGET="_top" TITLE="Behavioral Analyses">Behavioral Analyses</A>   ·   <A HREF="mice_to_men.htm" TARGET="_top" TITLE="Bridging Mice and Men">Bridging Mice and Men</A></div> </tD> </tR> </TABLE></div> <bR> <bR> <bR> </td> </tr></table></body>